Dionicol Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Thiamphenicol

Indications/Uses

Infections due to Salmonella sp, H influenzae (especially meningeal infection), rickettsia, lymphogranuloma-psittacosis, gm -ve bacteria.

Dosage/Direction for Use

Adult, childn, babies >2 wk 50 mg/kg in divided doses, to be taken 3-4 times daily. Premature babies, babies <2 wk 25 mg/kg in divided doses, to be taken 4 times daily.

Administration

Should be taken on an empty stomach: Take on an empty stomach 1 hr before or 2 hr after meals.

Contraindications

Hypersensitivity. Not for prophylaxis of bacterial infections or treatment of trivial infections, throat infections & flu. Not for hepatobiliary infections & gonorrhea. Patients w/ impaired liver & kidney function.

Special Precautions

Regular hematological exam should be performed in prolonged use. Treatment should be discontinued if reticulocytopenia, leucopenia, thrombocytopenia, or anemia occurs. Prolonged use. Patients w/ impaired kidney function. Pregnancy, lactation. May cause Grey’s syndrome in newborn babies (0-2 wk) & premature babies.

Adverse Reactions

Blood dyscrasia ie, aplastic anemia, hypoplastic anemia, thrombocytopenia, granulocytopenia; GI disturbances eg, nausea, vomiting, glossitis, stomatitis, diarrhea; hypersensitivity reactions eg, fever, skin rash, angioedema, urticaria; headache, mental depression, optic neuritis & Grey’s syndrome.

View ADR Reporting Link

Drug Interactions

May cause cross sensitivity w/ chloramphenicol. Dicoumarol, phenytoin, tolbutamide, phenobarb.

MIMS Class

Chloramphenicols

ATC Classification

J01BA02 - thiamphenicol ; Belongs to the class of amphenicols. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Dionicol caplet 500 mg

Packing/Price

10 × 10's

Form

Dionicol dry syr 125 mg/5 mL

Packing/Price

60 mL x 1's

Dionicol

thiamphenicol

Manufacturer:

Ifars