Amiclav Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Co-amoxiclav (amoxicillin & clavulanic acid). Per 625 mg caplet Amoxicillin 500 mg, clavulanic acid 125 mg. Per 5 mL dry syr Amoxicillin 250 mg, clavulanic acid 62.5 mg

Indications/Uses

Upper & lower resp tract, GUT, skin & soft tissue, bone & joint, dental & other infections eg, septic abortion, puerperal & intraabdominal sepsis.

Dosage/Direction for Use

Adult & childn >12 yr Mild to moderate infections 250 mg 3 times daily. Severe infections 500 mg 3 times daily. Childn Usual recommended dose: 25 mg/kg/day 8 hrly in divided doses. Dental infections Adult & childn >12 yr 250 mg 3 times daily for 5 days.

Contraindications

Hypersensitivity to penicillin. History of cholestatic jaundice/hepatic dysfunction. Neonates whose mothers are hypersensitive to penicillin or its derivatives.

Special Precautions

Avoid prolonged use. Severe hepatic impairment, moderate or severe renal impairment. Pregnancy & lactation.

Adverse Reactions

Nausea, vomiting, diarrhoea, indigestion, pseudomembranous colitis; candidiasis; hepatitis, cholestatic jaundice; urticarial & erythematous rashes, erythema multiforme, SJS, TEN, exfoliative dermatitis; nephritis; transient leucopenia, thrombocytopenia & hemolytic anemia.

View ADR Reporting Link

Drug Interactions

OCs, anticoagulants.

MIMS Class

Penicillins

ATC Classification

J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Amiclav caplet

Packing/Price

5 × 6's

Form

Amiclav dry syr

Packing/Price

60 mL x 1's

Amiclav

amoxicillin + clavulanic acid

Manufacturer:

Gracia Pharmindo