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Treatment de-escalation safe in patients with ERBB2-positive early breast cancer and high TILs
13 May 2026
byKanas Chan
De-escalation of chemotherapy dose and trastuzumab duration may not increase the risk of distant relapse or death in patients with ERBB2-positive (also referred to as HER2-positive) early breast cancer and tumour infiltrating lymphocyte (TIL) levels of ≥20 percent, according to a 10-year analysis of the phase III ShortHER trial.
Treatment de-escalation safe in patients with ERBB2-positive early breast cancer and high TILs
13 May 2026
‘Sandwich’ sequencing of adjuvant chemoradiation tied to less toxicity in advanced endometrial cancer
17 Mar 2026
Survival and clinical [Disease Link 9] outcomes in patients with advanced stage [Disease Link 10] endometrial cancer are [Disease Link 11] comparable among the different sequences of adjuvant chemotherapy and radiation therapy, a recent study has shown. However, “sandwich” therapy results in less chronic toxicity, which provides an opportunity for a better quality of life in survivorship.
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