
European Society for Medical Oncology Asia Congress 2025 (ESMO Asia 2025)
Singapore 05 December 2025 - 07 December 2025
Zongertinib shows promise in Asians with advanced HER2-mutant NSCLC
Treatment with zongertinib in Asian patients with advanced HER2-mutant nonsmall cell lung cancer (NSCLC), who have received prior systemic therapy, delivers robust efficacy and elicits an acceptable safety profile, consistent with the overall global analysis, reports a China study.

Tremelimumab plus durvalumab safe as first-line treatment for uHCC patients
The use of single tremelimumab (T) regular interval durvalumab (D), or STRIDE, results in a manageable safety profile in Asian patients with unresectable hepatocellular carcinoma (uHCC), as shown by the preliminary results of the SIERRA study.

Ivonescimab trumps tislelizumab for squamous NSCLC in HARMONi-6
In the phase III HARMONi-6 trial, ivonescimab plus chemotherapy significantly improved progression-free survival (PFS) compared with tislelizumab plus chemo as first-line treatment for individuals with advanced squamous non-small cell lung cancer (NSCLC).



