View Zymoplex overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Patients w/ personal or family history of blood clots of unknown cause; family history of illness that increases risk of blood clots. Concomitant use w/ anastrozole; any treatment for infertility; warfarin. Confirmed or suspected pregnancy.
May increase risk of formation of blood clots in the small vessels of the tissue flap in delayed breast reconstruction operation. Consider stopping treatment for a short period in case of planned surgery. May impair ability to drive or operate machinery. Women of childbearing potential should use adequate non-hormonal contraception during treatment & for an additional 2 mth after stopping treatment. Avoid pregnancy while on treatment & for 9 mth after stopping treatment. Lactation. Not for use in childn.
Nausea, fluid retention, skin rash, hot flushes, tiredness. Anaemia; changes in vision due to cataracts or changes to the retina; increased amounts of fats in the blood; allergic reactions; leg cramp; changes in the womb (including changes to its lining & benign growths); headache, lightheadedness; itching of the genitals; thinning of the hair; vomiting, diarrhoea, constipation; changes in blood tests of liver function; formation of fatty liver cells; muscle pain; sensory changes (including taste disorder & numbness or tingling in the skin); increased risk of blood clots (including clots in small vessels).
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