Adult men 50 mg as needed approx 1 hr before sexual activity. May be increased to 100 mg or decreased to 25 mg. Max dose: 100 mg. Max dosing frequency: Once daily. Renal or hepatic impairment Consider 25 mg dose, may be increased step-wise to 50-100 mg as necessary. Patients receiving concomitant treatment w/ CYP3A4 inhibitors except ritonavir Initially 25 mg. Patients on α-blocker treatment Initially 25 mg.
View Zygra overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Special Precautions
Not indicated for individuals <18 yr. Patients receiving α-blocker treatment should be stabilised on α-blocker therapy prior to initiating sildenafil treatment. Co-administration w/ ritonavir is not advised.