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Diclofenac is contraindicated in patients suffering from peptic ulcer disease/haemorrhage, or those having a history of gastrointestinal bleeding or perforation related to previous NSAID therapy, active, or history of recurrent peptic ulcer/haemorrhage, or history of hypersensitivity to diclofenac, aspirin or other NSAIDs.
Diclofenac is also contraindicated (i) in patients with severe heart failure and (ii) for the treatment of peri-operative pain in the setting of coronary artery bypass graft surgery.
Similar to other NSAIDs, diclofenac should not be prescribed to patients having attacks of asthma and allergic reaction, such as allergic rhinitis, urticaria, angioedema or skin rash that are precipitated by aspirin or other NSAIDs and during pregnancy.
