CNS depressant effects. Potential to cause severe allergic reactions & complex sleep-related behaviours. Long-term use is not recommended. Risk of next-day psychomotor impairment. Patients w/ compromised resp function; hepatic impairment; elderly; patients w/ history of drug or alcohol abuse; patients exhibiting symptoms of depression. Not recommended for the primary treatment of psychotic illness. Tolerance, abuse &/or physical & psychological dependence may develop. Risk of w/drawal phenomena or rebound upon abrupt discontinuation. May induce anterograde amnesia. Risk of other psychiatric & paradoxical reactions eg, restlessness, exacerbated insomnia, agitation, irritability, aggression, delusion, anger, nightmares, hallucinations, psychosis, abnormal behaviour & other adverse behavioural effects, especially in the elderly. Reports of somnambulism & associated behaviours. Concomitant use w/ opioids. Do not take together w/ alcohol or other medicines that have an effect on mental function &/or CNS. Major influence on the ability to drive & use machines. Do not drive or perform activities that require mental alertness until 8 hr after taking zolpidem. Not recommended in pregnancy & lactation.
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