Xylocaine Pump Spray

Prevention of pain associated w/ otorhinolaryngology; obstet; introduction of instruments, tubes & catheters into the resp & digestive tract; dental practice.

Debilitated or elderly patients, childn >12 yr, acutely ill patients or patients w/ sepsis should be given doses commensurate w/ their age, wt & physical condition. Dose should not exceed 3 mg/kg in childn <12 yr. Dose should be reduced to 1.5 mg/kg when used mainly in the larynx & trachea. Less concentrated soln is recommended in childn <3 yr. Otorhinolaryngology 3 metered doses for puncture of the maxillary sinus or other minor surgical procedures. Obstet Up to 20 metered doses during delivery. Introduction of instruments, tubes & catheters into the resp & digestive tract Up to 20 metered doses for procedures in the pharynx, larynx & trachea. Up to 400 mg may be administered during prolonged procedures. Total dose should not exceed 400 mg when combined w/ other lidocaine products. Dose should not exceed 20 metered doses w/ applications mainly to the larynx, trachea & bronchi. Dental practice 1-5 metered doses to the mucous membranes.

Hypersensitivity to amide-type local anaesth.

Excessive doses or short intervals between doses may result in high plasma levels & serious adverse effects. Should be used w/ caution in patients w/ wounds or traumatized mucosa in the region of the proposed application. Higher blood conc may occur in paralysed patients under general anaesth than in spontaneously breathing patients. Oropharyngeal use may interfere w/ swallowing & enhance danger of aspiration. Numbness of the tongue or buccal mucosa may increase danger of biting trauma. Patients w/ CV disease & heart failure, patients w/ partial or complete heart block, elderly patients & patients in poor general health, & patients w/ advanced liver disease or severe renal dysfunction require special attention to prevent potentially dangerous side effects if the dose or administration is likely to result in high blood levels. Consider ECG monitoring in patients treated w/ class III antiarrhythmics (eg, amiodarone). Should not be used on cuffs of endotracheal tubes made of plastic. Probably porphyrinogenic & should only be prescribed to patients w/ acute porphyria on strong or urgent indications. May have a very mild effect on mental function & may temporarily impair locomotion & coordination.

Local reactions, allergic reactions, acute systemic toxicity.

Additive toxic effects w/ agents structurally related to local anaesth (eg, mexiletine, tocainide). Caution w/ class III antiarrhythmics (eg, amiodarone). Drugs that reduce clearance of lidocaine (eg, cimetidine, β-blockers) may cause potentially toxic plasma conc when lidocaine is given in repeated high doses over a long period.

Anaesthetics - Local & General

N01BB02 - lidocaine ; Belongs to the class of amides. Used as local anesthetics.

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