Xylocaine Jelly

As a surface anaesth & lubricant for the male & female urethra during cystoscopy, catheterisation, exploration by sound & other endourethral procedures; for nasal & pharyngeal cavities in endoscopic procedures eg, gastroscopy & bronchoscopy; during proctoscopy & rectoscopy; for tracheal intubation. Symptomatic treatment of pain in connection w/ cystitis & urethritis. Pain relief after circumcision in childn.

Debilitated or elderly patients, childn >12 yr, acutely ill patients or patients w/ sepsis should be given doses commensurate w/ their age, wt & physical condition. Dose should not exceed 6 mg/kg in childn <12 yr. No more than 4 doses should be given in a 24-hr period. Surface anaesth of the adult male urethra Instill 20 mL for adequate analgesia. When anaesth is especially important (eg, during sounding or cystoscopy), a larger quantity of jelly (eg, 30-40 mL) may be instilled in 3-4 portions & allowed to act for 10 min before insertion of the instrument. Surface anaesth of the adult female urethra Instill 5-10 mL in small portions to fill the whole urethra. To obtain adequate anaesth, several min should be allowed to elapse prior to performing urological procedures. Endoscopy Instill 10-20 mL for adequate analgesia. When combined w/ other lidocaine products (eg, for bronchoscopy), total dose should not exceed 400 mg. Proctoscopy & rectoscopy Instill up to 20 mL for anal & rectal procedures. Total dose should not exceed 400 mg. Lubrication for endotracheal intubation Apply about 2 mL to the surface of the tube just prior to insertion. Avoid introduction into the lumen of the tube.

Hypersensitivity to amide-type local anaesth or history thereof. Hypersensitivity to methyl &/or propyl parahydroxybenzoate or their metabolite PABA. Patients allergic to ester local anaesth or their metabolite PABA.

Excessive doses or short intervals between doses can result in high plasma levels & serious adverse effects. Should be used w/ caution in patients w/ traumatized mucosa &/or sepsis in the region of the proposed application. Oropharyngeal use may interfere w/ swallowing & enhance danger of aspiration. Numbness of the tongue or buccal mucosa may increase danger of biting trauma. Consider ECG monitoring in patients being treated w/ class III antiarrhythmics (eg, amiodarone). Patients w/ partial or complete heart block, elderly patients & patients in poor general health, & patients w/ advanced liver disease or severe renal dysfunction require special attention to prevent potentially dangerous side effects if the dose or administration is likely to result in high blood levels. Probably porphyrinogenic & should only be prescribed to patients w/ acute porphyria on strong or urgent indications. May have a very mild effect on mental function & may temporarily impair locomotion & coordination.

Local reactions, allergic reactions, acute systemic toxicity.

Additive toxic effects w/ agents structurally related to local anaesth. Caution w/ class III antiarrhythmics. Drugs that reduce clearance of lidocaine (eg, cimetidine or β-blockers) may cause potentially toxic plasma conc when lidocaine is given in repeated high doses over a long period.

Anaesthetics - Local & General

N01BB02 - lidocaine ; Belongs to the class of amides. Used as local anesthetics.

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