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Each vial contains 120 mg of denosumab in 1.7 ml of solution (70 mg/ml).
Denosumab is a human monoclonal IgG2 antibody produced in a mammalian cell line (Chinese hamster ovary cells) by recombinant DNA technology.
Excipient with known effects: Each 1.7 ml of solution contains 78 mg sorbitol (E420).
Excipients/Inactive Ingredients: Glacial acetic acid*, Sodium hydroxide (for pH adjustment)*, Sorbitol (E420), Polysorbate 20, Water for injections.
*Acetate buffer is formed by mixing acetic acid with sodium hydroxide.
