1 tablet of Vastarel MR twice daily during meals.
Renal Impairment: In patients with moderate renal impairment (creatinine clearance 30-60 mL/min) (see Precautions and Pharmacology: Pharmacokinetics under Actions), the recommended dose is 1 tablet Vastarel MR in the morning during breakfast.
Elderly: Elderly patients may have increased trimetazidine exposure due to age-related decrease in renal function (see Pharmacology: Pharmacokinetics under Actions). In patients with moderate renal impairment (creatinine clearance 30-60 mL/min), the recommended dose is 1 tablet Vastarel MR in the morning during breakfast.
Dose titration in elderly patients should be exercised with caution (see Precautions).
Children: The safety and efficacy of trimetazidine in children <18 years have not been established. No data are available.