Varilrix Caution For Usage

Use and Handling: Due to minor variations of its pH, the colour of the reconstituted vaccine may vary from peach to pink coloured solution.
The solvent and the reconstituted vaccine should be inspected visually for any foreign particulate matter and/or variation of physical aspect prior to administration. In the event of either being observed, discard the solvent or the reconstituted vaccine.
Instructions for reconstitution of the vaccine with solvent presented in ampoules: VARILRIX must be reconstituted by adding the contents of the supplied container of solvent to the vial containing the powder. After the addition of the solvent to the powder, the mixture should be well shaken until the powder is completely dissolved in the solvent.
After reconstitution, the vaccine should be used promptly.
A new needle should be used to administer the vaccine.
Withdraw the entire contents of the vial.
Instructions for reconstitution of the vaccine with solvent presented in pre-filled syringe: VARILRIX must be reconstituted by adding the entire content of the pre-filled syringe of solvent to the vial containing the powder.
1. Holding the syringe barrel in one hand (avoid holding the syringe plunger), unscrew the syringe cap by twisting it anticlockwise.
2. To attach the needle to the syringe, twist the needle clockwise into the syringe until it lock.
3. Remove the needle protector, which on occasion can be a little stiff.
Add the solvent to the powder. After the addition of the solvent to the powder, the mixture should be well shaken until the powder is completely dissolved in the solvent.
After reconstitution, the vaccine should be used promptly.
A new needle should be used to administer the vaccine.
Withdraw the entire contents of the vial.
Any unused product or waste material should be disposed of in accordance with local requirements.
Incompatibilities: VARILRIX should not be mixed with other vaccines in the same syringe.