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Administration: Sezstad 10 is administered orally at any time of the day, with or without food.
The patient should be on an appropriate lipid-lowering diet and should continue on this diet during treatment.
Concomitant lipid-lowering therapy: When Sezstad 10 is added to a statin, either the indicated usual initial dose of that particular statin or the already established higher statin dose should be continued. In this setting, the dosage instructions for that particular statin should be consulted.
Co-administration with bile acid sequestrants: Dosing of ezetimibe should occur either at least 2 hours before or 4 hours after administration of a bile acid sequestrant.
Dosage: The recommended dose is one tablet daily.
Children and adolescents ≥10 years: No dosage adjustment is required.
Children <10 years: Ezetimibe is not recommended for use in children below age 10 due to insufficient data on safety and efficacy.
Use in the elderly: No dosage adjustment is required for elderly patients.
Patients with hepatic impairment or renal impairment: No dosage adjustment is necessary in patients with mild hepatic impairment or renal impairment.
