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REXULTI is available in 0.5 mg, 1 mg, 2 mg and 3 mg tablet strengths.
Proper name: brexpiprazole.
Chemical name: 7-{4-[4-(1-Benzothiophen-4-yl)piperazin-1-yl]butoxy}quinolin-2(1H)-one.
Molecular formula: C25H27N3O2S.
Molecular mass: 433.57g/mol.
Physicochemical properties: Brexpiprazole is non-hygroscopic, with white to off-white crystals or crystalline powders, and a melting point of 183°C (decomposition). Brexpiprazole is a weakly basic compound with a pKa of 7.8. It is practically insoluble in water, and the solubility of the drug substance at pH 2 is 0.56 mg/mL, at pH 4 is 0.13 mg/mL, and at pH 6 is 0.0020 mg/mL.
Excipients/Inactive Ingredients: corn starch, hydroxypropyl cellulose, hypromellose, lactose monohydrate, low-substituted hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, and talc.
Colourants: ferric oxide red (0.5 mg, 3 mg), ferric oxide yellow (0.5 mg, 1mg, 2 mg), ferrosoferric oxide (2 mg, 3 mg), and titanium dioxide.
