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Pharmacotherapeutic group: Antifungals for topical use. ATC code: D01AA01.
Pharmacology: Pharmacodynamics: Nystatin is an antifungal antibiotic active against a wide range of yeasts and yeast-like fungi, including Candida albicans.
Pharmacokinetics: Absorption: Nystatin is formulated in oral and topical dosage forms and is not systemically absorbed from any of these preparations.
Gastrointestinal absorption of nystatin is insignificant.
Elimination: Most orally administered nystatin is passed unchanged in the stool.
Toxicology: Preclinical safety data: No long-term animal studies have been performed to evaluate the carcinogenic potential of nystatin. No studies have been performed to determine the mutagenicity of nystatin or its effect on male or female fertility.
