Do not use pms-Duloxetine if: The patient is younger than 18 years of age.
The patient is allergic to any of the ingredients of pms-Duloxetine (see Description).
The patient has a liver impairment or disorder. A liver disorder is when the liver can no longer carry out its normal function.
The patient has severe kidney disease.
The patient is taking or has just stopped taking any of these drugs in the last 14 days: monoamine oxidase inhibitors (MAOIs) such as phenelzine or moclobemide, to treat depression; linezolid to treat infection(s).
The patient has been given a dye called methylene blue during surgery in the last 14 days.
The patient is on a drug or has been on a drug to manage psychosis (serious mental illness) called thioridazine.
The patient is taking a medication to treat depression, like fluvoxamine, a potent CYP1A2 inhibitor.
The patient is taking certain antibiotics, like ciprofloxacin or enoxacin.