pms-Citalopram Description

Each film-coated tablet contains 20 mg citalopram (as citalopram hydrobromide).
Proper name: Citalopram hydrobromide.
Chemical name: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran-carbonitrile monohydrobromide; or (1RS)-1-[3-(dimethylamino)propyl-1-(4-fluorophenyl)-1,3-dihydro-isobenzofurane-5-carbonitrile hydrobromide; or 1-[3-(Dimethylamino)propyl]-1-(p-fluorophenyl)-5-phthalancarbonitrile monohydrobromide.
Molecular formula: C₂₀H₂₂BrFN₂O.
Molecular mass: 405.31 g/mol.
Physicochemical properties: White or almost white crystalline powder. Odourless or almost odourless. Its melting point is between 184°C and 188°C, its pH between 5.5 to 6.5 (0.5% w/v in water), and its pKa is 9.5 (microtitration). It is sparingly soluble in water, soluble in ethanol, freely soluble in chloroform and very slightly soluble in diethylether.
Excipients/Inactive Ingredients: Colloidal silicon dioxide, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate and titanium dioxide.