Pantoloc Control

Short-term treatment of reflux symptoms (eg, heartburn, acid regurgitation) in adults.

1 tab daily. Max dose: 20 mg daily.

Should be taken on an empty stomach: Take before meals, at the same time every day. Swallow whole w/ water. Do not chew/break.

Hypersensitivity. Concomitant use w/ HIV PIs eg, atazanavir, nelfinavir.

Should not be taken for >4 wk or as preventive measure. Risk of reduced vit B₁₂ absorption, & vit B₁₂ deficiency if body stores of vit B₁₂ are already low. Consider monitoring of Mg levels prior to treatment initiation & periodically during treatment. Treatment may lead to slightly increased risk of GI infections eg, Salmonella, Campylobacter, & possibly Clostridium difficile. Long-term therapy (≥1 yr) & multiple daily doses may be associated w/ increased risk for osteoporosis-related fractures of the hip, wrist or spine. Subacute cutaneous lupus erythematosus (SCLE) after previous PPI treatment may increase risk of SCLE w/ other PPIs. Reports of serious skin reactions including SJS, TEN, DRESS & erythema multiforme. Caution in patients treated for heartburn or indigestion continuously for ≥4 wk; patients >55 yr taking non-prescription indigestion treatment daily or w/ any new or recently changed reflux symptoms; patients w/ previous gastric ulcer or stomach surgery; patients w/ liver problems or jaundice; patients w/ regular serious complaints or conditions; patients due to have endoscopy, C-urea breath test, or chromogranin A blood test; patients w/ history of skin reaction after treatment w/ medicine that reduces stomach acid. Concomitant use w/ MTX. Patients who experience dizziness or disturbed vision should not drive or use machines. Should not be taken while pregnant or breast-feeding. Should not be used by childn & adolescents <18 yr.

Benign polyps in the stomach.

May stop other medicines from working properly (eg, atazanavir, nelfinavir, ketoconazole, warfarin, phenprocoumon). Elevated & prolonged serum levels of MTX &/or its metabolite hydroxymethotrexate. Do not co-administer w/ H₂ antagonists (eg, ranitidine, famotidine) or other PPIs (eg, omeprazole, lansoprazole, rabeprazole). Caution in patients due to have tetrahydrocannabinol urine test.

Antacids, Antireflux Agents & Antiulcerants

A02BC02 - pantoprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

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