Discontinue use if patient is completely symptom-free; if lesions occur, especially in sun-exposed areas of the skin, & accompanied by arthralgia; if patient get a skin rash especially in areas exposed to sun. Not to be taken >4 wk. Patients treated for heartburn or indigestion continuously for ≥4 wk. History of gastric ulcer or stomach surgery. Patients >55 yr taking nonprescription indigestion treatment daily; w/ new or recently changed reflux symptoms. Patients due to have endoscopy, C-urea test, & Chromogranin A test. Risk of vit B
12 deficiency. May lead to slightly increased risk of GI infections eg, Salmonella & Campylobacter & possibly
Clostridium difficile. Increased risk for osteoporosis-related fractures of the hip, wrist or spine in long-term (≥1 yr) & multiple daily dose. Patients should use the lowest dose & shortest duration of therapy appropriate to the condition being treated. Symptomatic & asymptomatic hypomagnesemia. Consider monitoring Mg levels prior to treatment initiation & periodically. Concomitant use w/ HIV PIs; MTX. May affect ability to drive & use machines. Patients w/ liver problems or jaundice. Not to be used during pregnancy or breastfeeding. Not to be used by childn & adolescents <18 yr.
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