Always use the lowest effective dose for the shortest period of time. Overdose may cause liver failure. Do not use w/ any other paracetamol-containing prescription or non-prescription medicines. Avoid use w/ alcohol. Should not be taken by patients w/ rare hereditary problems of fructose intolerance. Caution in underweight or malnourished patients; patients w/ severe infection; patients w/ liver or kidney impairment. Not recommended in childn <3 mth.