As with other medicinal products for colds, Otrivin can lead to sleep and vision problems or episodes of dizziness which are evidence of oversensitivity to the product.
Consult a doctor if these effects are very disruptive; cold persists or gets worse; or other problems appear.
Otrivin must be used with care in the case of hypertension, cardio-vascular disease, thyroid hyperactivity, enlarged prostate, phaeochromocytoma (a tumour of the adrenal glands) or diabetes (Diabetes mellitus).
Otrivin should not be used if the patient is currently taking a MAO inhibitor (a medicine against depression), or has taken one within the last 14 days.
Otrivin should also not be used if the patient is taking certain anti-depressants (tricyclic or tetracyclic anti-depressants).
Otrivin must not be used for more than a week without medical advice because over a longer period of use, rebound congestion of the nasal mucosa (rhinitis medicamentosa) may appear. This would be very similar to the symptoms of cold.
Patient should inform the doctor, pharmacist or chemist if suffering from another medical condition; allergic; already taking or using other medicinal products either internally or externally (even when as self-medication).