In the event of inappropriate administration (overdose and/or infusion rate higher than recommended), signs of hypervolemia and acidosis may occur.
An excessively fast infusion or administration of an inappropriately large volume of the product may cause nausea, vomiting, chills and electrolyte disturbances. In such situations the infusion must be stopped immediately.
Hyperglycaemia, glucosuria, and a hyperosmolar syndrome may develop if glucose infusion rate exceeds clearance.
The reduced or limited ability to metabolise lipids may result in a "fat overload syndrome" the results of which are usually reversible after the infusion of the lipid emulsion is stopped (see also Adverse Reactions).
In some serious cases, haemodialysis, hemofiltration or haemodiafiltration may be necessary.