Ninlaro Special Precautions

Before or during treatment with NINLARO, caution should be exercised in: patients who have a history of bleeding; patients who have persistent nausea, vomiting or diarrhoea; patients who have a history of nerve problems, including tingling and numbness; patients who have a history of swelling; patients who have a persistent rash or Stevens-Johnson syndrome; patients who have or have had liver or kidney problems as the dose may have to be adjusted; patients who have or have had thrombotic microangiopathy or thrombotic thrombocytopenic purpura. The occurrence of fatigue, fever, bruising, bleeding, decreased urination, swelling, confusion, vision loss, and seizures should be monitored.
Patients should be examined and monitored closely during treatment. Before starting NINLARO and during treatment, blood tests should be performed.
Driving and using machines: NINLARO may affect the ability to drive or use machines. Tiredness and dizziness may occur while taking NINLARO. Patients should not drive or operate machines if these side effects occur.
Use in Children: NINLARO is not recommended for use in children and adolescents aged under 18 years.