Neupro Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Caution For Usage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Rotigotine

Indications/Uses

Treatment of the signs & symptoms of early-stage idiopathic Parkinson's disease as monotherapy or in combination w/ levodopa ie, over the course of the disease, through to late stages.

Click to view Neupro detailed prescribing information

Dosage/Direction for Use

Leave patch on the skin for 24 hr, then ensure to take old patch off before putting new one on a different area of the skin each day. Change patches at about the same time every day. Monotherapy (early stage of Parkinson's disease) Initially one 2-mg patch daily. Increase by 2 mg wkly from the 2nd wk until maintenance dose is reached. Usual maintenance dose: 6-8 mg daily. Max dose: 8 mg daily. Combination w/ levodopa (advanced stage of Parkinson's disease) Initially one 4-mg patch daily. Increase by 2 mg wkly from the 2nd wk until maintenance dose is reached. Usual maintenance dose: 8-16 mg daily. Max dose: 16 mg daily.

Click to view Neupro detailed prescribing information

Overdosage

View Neupro overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity. Patients undergoing MRI or cardioversion.

Click to view Neupro detailed prescribing information

Special Precautions

Regularly check BP & eyesight during use. Gradually reduce or stop treatment to avoid dopamine agonist w/drawal syndrome or NMS. Avoid sunlight & solarium exposure on areas of skin showing any kind of skin reaction caused by the patch. Risk of dystonia or pleurothotonus (Pisa syndrome); changes in behaviour & abnormal thinking. Do not stick the patch on the same area of skin twice w/in 14 days. Do not stick the patch on broken, damaged, red, or irritated skin. Do not cut the patches into pieces. Contains Na metabisulphite (E223), which may rarely cause severe hypersensitivity reactions & bronchospasm. Patients who lose consciousness or feel dizzy should not drive or use machines. Caution in patients w/ serious liver problems. Do not use during pregnancy. Do not breast-feed during treatment. Do not give to childn <18 yr.

Click to view Neupro detailed prescribing information

Use In Pregnancy & Lactation

Click to view Neupro detailed prescribing information

Adverse Reactions

Headache; feeling sleepy or dizzy; nausea, vomiting; skin reactions under the patch eg, redness & itching. Falling; hiccups; wt loss; swelling of legs & feet; feeling weak or tired; palpitation; constipation, dry mouth, heartburn; redness, increased sweating, itching; vertigo; hallucinations; low BP when standing up, high BP; difficulty falling asleep, sleep disorder, difficulty sleeping, nightmare, unusual dreams; dyskinesia; fainting, feeling dizzy when standing up because of fall in BP; unable to resist impulse to perform harmful action involving excessive gambling, repetitive meaningless actions, uncontrolled shopping or spending too much; binge eating, compulsive eating.

Drug Interactions

Decreased effect w/ antipsychotics & metoclopramide. Potential interaction w/ sedatives (eg, benzodiazepines), antidepressants, & alcohol. Worsened orthostatic hypotension w/ antihypertensives.

Click to view Neupro detailed prescribing information

Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Neupro detailed prescribing information

Description

View Neupro description for details of the chemical structure and excipients (inactive components).

Action

View Neupro mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antiparkinsonian Drugs

ATC Classification

N04BC09 - rotigotine ; Belongs to the class of dopamine agonists. Used in the management of Parkinson's disease.

Regulatory Classification

P₁S₁S₃

Presentation/Packing

Form

Neupro 24 hr transdermal patch 2 mg

Packing/Price

10 cm2 x 28 × 1's

Form

Neupro 24 hr transdermal patch 4 mg

Packing/Price

20 cm2 x 28 × 1's

Form

Neupro 24 hr transdermal patch 6 mg

Packing/Price

30 cm2 x 28 × 1's

Form

Neupro 24 hr transdermal patch 8 mg

Packing/Price

40 cm2 x 28 × 1's

Neupro

rotigotine

Manufacturer:

UCB

Distributor:

Zuellig

Agencia Lei Va Hong