Because the systemic bioavailability of NASONEX is <1% (using a sensitive assay with a lower quantitation limit of 0.25 pg/ml) NASONEX, overdose is unlikely to require any therapy other than observation, followed by initiation of the appropriate prescribed dosage.
Inhalation or oral administration of excessive doses of corticosteroids may lead to suppression of hypopituitary-adrenal (HPA) axis function.