The clinician's experience and knowledge of the patient's physical status are of importance in calculating the required dose. The lowest dose required for adequate anaesthesia should be used. Duration varies with dose, while segmental spread may be difficult to predict, especially with the isobaric (plain) solution.
The dose should be reduced in the elderly and in patients in the late stages of pregnancy. (See Table 1.)
The recommended injection site is the L3-L4 intervertebral space.
Children up to 40 kg: Marcain Spinal Heavy may be used in children.
One of the differences between small children and adults is a relatively high CSF volume in infants and neonates, requiring a relatively larger dose/kg to produce the same level of block as compared to adults. (See Table 2.)
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