LIPANTHYL PENTA 145 is indicated as an adjunct to diet and other non-pharmacological treatment (e.g. exercise, weight reduction) for the following conditions: Severe hypertriglyceridemia with or without low HDL cholesterol; Mixed hyperlipidemia when a statin is contraindicated or not tolerated; Mixed hyperlipidemia in patients at high cardiovascular risk in addition to a statin when triglycerides and HDL cholesterol are not adequately controlled.