Monoamine oxidase inhibitors and LEVOMED should not be given concomitantly, and these inhibitors must be discontinued at least two weeks prior to initiating therapy with LEVOMED.
LEVOMED is contraindicated in patients with known hypersensitivity to this drug, and in narrow angle glaucoma.
Because Levodopa may activate a malignant melanoma, it should not be used in patients with suspicious undiagnosed skin lesions or a history of melanoma.