Each mL of Latanoprost Ophthalmic Solution contains 50 micrograms of latanoprost. Benzalkonium chloride, 0.02% is added as a preservative. One drop contains approximately 1.5 μg of latanoprost.
Latanoprost is a prostaglandin F2α analogue. Its chemical name is isopropyl-(Z)-7[(1R,2R,3R,5S)3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoate. Its molecular formula is C26H40O5.
Latanoprost is a colorless to slightly yellow oil that is very soluble in acetonitrile and freely soluble in acetone, ethanol, ethyl acetate, isopropanol, methanol and octanol. It is practically insoluble in water.
Latanoprost Ophthalmic Solution is supplied as a sterile, isotonic, buffered aqueous solution of latanoprost with a pH of approximately 6.7 and an osmolality of approximately 267 mOsmol/kg.
Excipients/Inactive Ingredients: Disodium hydrogen phosphate anhydrous, sodium chloride, sodium dihydrogen phosphate monohydrate, and water for injection.