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The effects of overdose on lansoprazole in humans are not known (although the acute toxicity is likely to be low) and, consequently, instruction for treatment cannot be given. However, daily doses of up to 180 mg lansoprazole orally and up to 90 mg intravenously have been administered in trials without significant undesirable effects.
In the case of suspected overdose the patient should be monitored. Lansoprazole is not significantly eliminated by haemodialysis. If necessary gastric emptying, charcoal and symptomatic therapy is recommended.
