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Hypersensitivity to donanemab or to any of the excipients listed in Description.
Baseline MRI findings of prior intracerebral haemorrhage greater than 1 cm, more than 2 microhaemorrhages, superficial siderosis or vasogenic oedema (ARIA-E), which are suggestive of cerebral amyloid angiopathy (CAA).
Severe white matter disease.
Any finding that could prevent a satisfactory MRI evaluation for safety monitoring.
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