Like all medicines, Ketrel 0.05% cream can cause side effects, although not everybody gets them.
In the first weeks of treatment, there may be worsening of the acne, in particular the appearance of small white-headed pustules.
This is normal. It is caused by the quicker elimination of the microcysts ("white heads") that were forming in the deeper layers of the skin.
Local side effects may occasionally appear in the form of irritations: diffuse redness, tingling, dryness of the skin, mild flaking (peeling skin).
These reactions are directly linked to the product's activity and disappear if a longer period is left between applications (e.g. 1 application every 2 days).
Some ingredients in this medicine, other than the active ingredient, can cause reactions (see Important information about some of the ingredients of this medicine under Precautions).
Patient should talk to the doctor or pharmacist if he/she gets any side effects. This includes any possible side effects not listed in this monograph.