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Serious hypersensitivity reaction to INVOKANA, such as anaphylaxis or angioedema [see Hypersensitivity Reactions under Precautions and Clinical Studies Experience and Postmarketing Experience under Adverse Reactions].
Severe renal impairment (eGFR less than 30 mL/min/1.73 m2), end stage renal disease (ESRD), or patients on dialysis [see Acute Kidney Injury and Renal Impairment under Precautions].
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