Special precautions for disposal and other handling: Herceptin should be inspected visually to ensure there is no particulate matter or discolouration prior to administration.
Herceptin is for single-use only.
As Herceptin does not contain any antimicrobial-preservative, from a microbiological point of view, the medicine should be used immediately. If not used immediately, preparation should take place in controlled and validated aseptic conditions. After transfer of the solution to the syringe, it is recommended to replace the transfer needle by a syringe closing cap to avoid drying of the solution in the needle and not compromise the quality of the medicinal product. The hypodermic injection needle must be attached to the syringe immediately prior to administration followed by volume adjustment to 5 mL.
Disposal of unused/expired medicines: The release of pharmaceuticals in the environment should be minimized. Medicines should not be disposed of via wastewater and disposal through household waste should be avoided.
Incompatibilities: Herceptin subcutaneous formulation is a ready to use solution which should not be mixed or diluted with other products.