Pharmacology: Loratadine is a long-acting tricyclic antihistamine with selective, peripheral H1-receptor activity.
Pseudoephedrine HCl, one of the naturally occurring alkaloids of Ephedra and an orally administered vasoconstrictor, produces a gradual but sustained decongestant effect facilitating shrinkage of congested mucosa in upper respiratory areas. The mucous membrane of the respiratory tract is decongested through the action of the sympathetic nerves.