Fludalym Side Effects

Like all medicines, Fludalym can cause side effects, although not everybody gets them. If the patient is not sure what the adverse reactions as follows are, ask the doctor to explain them to the patient.
Some side effects can be life-threatening. If the patient has difficulty breathing, has a cough, or has chest pain with or without fever. These may be signs of an infection of the lungs.
If the patient notices any unusual bruising, more bleeding than usual after injury or if the patient seems to be catching a lot of infections. These may be caused by a reduced number of blood cells. This may also lead to an increased risk of (serious) infections, caused by organisms, that usually do not cause disease in healthy persons (opportunistic infections) including a late reactivation of viruses, for example herpes zoster.
If the patient notices any pain in the side, blood in the urine, or reduced amount of urine. These may be signs of tumour lysis syndrome (see Precautions).
If the patient notices any skin and/or mucous coat reaction with redness, inflammation, blistering and tissue break down. These may be signs of a severe allergic reaction (Lyell's syndrome, Stevens-Johnson syndrome).
If the patient has palpitations (if the patient suddenly becomes aware of his/her heartbeat) or chest pain. These may be signs of heart problems.
Tell the doctor immediately, if the patient notices any of these effects.
As follows are the list of possible side effects by how common they are. The rare side effects (less than 1 in every 1000 patients) were mainly identified from post-marketing experience.
Very common means 1 or more in every 10 patients are likely to get these: infections (some serious); infections due to depressed immune system (opportunistic infections); infection of the lungs (pneumonia) with possible symptoms like breathing difficulties and/or cough with or without fever; reduction in the number of blood platelets (thrombocytopenia) with the possibility of bruising and bleeding; lowered white blood cell count (neutropenia); lowered red blood cell count (anaemia); cough; vomiting, diarrhea, feeling sick (nausea); fever; feeling tired (fatigue); weakness.
Common means between 1 and 10 in every 100 patients are likely to get these: other blood related cancers (myelodysplastic syndrome, acute myeloid leukaemia). Most patients with these conditions were previously, or at the same time or later treated with other cancer drugs (alkylating agents, topoisomerase inhibitors) or radiation therapy; bone marrow depression (myelosuppression); severe loss of appetite leading to weight loss (anorexia); numbness or weakness in limbs (peripheral neuropathy); disturbed vision; inflammation inside of the mouth (stomatitis); skin rash; swelling due to excessive fluid retention (oedema); inflammation of the mucous coat of the digestive system from the mouth to the anus (mucositis); chills; generally feeling unwell.
Uncommon means between 1 and 10 in every 1,000 patients are likely to get these: autoimmune disorder (see Precautions); tumour lysis syndrome (see Precautions); confusion; lung toxicity; scaring through out the lungs (pulmonary fibrosis), inflammation of the lungs (pneumonitis), shortness of breath (dyspnoea); bleeding in the stomach or intestines; abnormal levels of the liver or pancreas enzymes.
Rare means less than 10 in every 10,000 patients are likely to get these: disorders of the lymph system due to a viral infection (EBV-associated lymphoproliferative disorder); coma; seizures; agitation; blindness; inflammation or damage of the nerve of the eyes (optic neuritis; optic neuropathy); heart failure; irregular heart beat (arrhythmia); skin cancer; skin and/or mucous coat reaction with redness, inflammation, blistering and tissue break down (Lyell's syndrome, Stevens-Johnson syndrome).
Frequency not known: inflammation of the bladder, which can cause pain when passing urine, and can lead to blood in the urine (haemorrhagic cystitis); bleeding in the brain; bleeding in the lungs.
If any side effects get serious, or if the patient notices any side effects not listed, please tell the doctor.