Extrapan gel should not used: If the patient is allergic (hypersensitive) to ibuprofen or any of the other ingredients of Extrapan gel; If the patient is allergic to other drugs of the same category or to Ibuprofen; On mucous membranes and eyes; With babies and children except on the advice of a doctor; On inflamed skin or on wounds; The third trimester of pregnancy, because of risks of premature closure of the ductus arteriosus, and prolonged parturition.