Discontinue treatment immediately in case of serious hypersensitivity reaction. No safety data in patients w/ major CV diseases. Minor influence on ability to drive & use machines. Preferable to avoid use during pregnancy. Consider use during breast-feeding only if clinically needed. Safety & efficacy in childn 6-18 yr have not yet been established. No relevant use in childn <6 yr. Limited information in elderly ≥65 yr.