Efficort Special Precautions

Efficort Cream is for cutaneous use only.
General: The prolonged use on the face of high-potency corticosteroids can give rise to a corticosteroid-induced dermatitis which is paradoxically corticosteroid-responsive. A rebound effect is observed at each interruption of treatment. Progressive and particularly difficult withdrawal is then required.
Due to the possibility of absorption of corticosteroids into the general circulation, treatment of large areas or under occlusion may give rise to the effects of systemic corticosteroid therapy, particularly in the infant and small child. These effects consist of Cushing syndrome and growth inhibition: these untoward effects disappear upon interruption of treatment but abrupt withdrawal can result in acute adrenal insufficiency. It is preferable to avoid use of corticosteroids in the infant and particular attention must be given to the likelihood of spontaneous occlusion. In the case of a bacterial or fungal infection of a corticosteroid-responsive dermatosis, either a specific antimicrobial treatment must precede the use of the corticosteroid or possibly, and in only certain cases, a combination of corticosteroid plus specific treatment may be used.
If local intolerance occurs, treatment must be interrupted and the cause investigated.
In the event of application to the eyelid, the duration of treatment must be limited. Prolonged application exposes the patient to the risk of ptosis or glaucoma and a rebound effect can be observed.
Effects on the ability to drive and use machines: Based on the pharmacodynamic profile and extensive clinical experience, performance related to driving and using machines should not be affected.