Shelf life: After dilution: When prepared as directed, infusion solutions of Cyramza contain no antimicrobial preservatives.
Chemical and physical in-use stability of Cyramza in sodium chloride 9 mg/ml (0.9%) solution for injection has been demonstrated for 24 hours at 2°C to 8℃ or for 4 hours at room temperature (below 30℃). From a microbiological point of view, the product should be used immediately. If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2℃ to 8℃, unless dilution has taken place in controlled and validated aseptic conditions.
Special precautions for storage: Store in a refrigerator (2°C-8°C).
Do not freeze.
Keep the vial in the outer carton in order to protect from light.
For storage conditions after dilution of the medicinal product, see Shelf life as previously mentioned.