High potential for abuse & misuse; assess patient's risk for abuse, misuse & addiction before prescribing & throughout treatment. Avoid use in patients w/ known structural cardiac abnormalities, cardiomyopathy, serious cardiac arrhythmia, CAD, or other serious cardiac disease. Monitor patients for HTN & tachycardia. May exacerbate symptoms of behavior disturbance & thought disorder in psychotic patients. Screen patients at risk for developing manic episode (eg, comorbid or history of depressive symptoms or family history of suicide, bipolar disorder or depression). Discontinue if psychotic or manic symptoms occur in patients w/o prior history of psychotic illness or mania; presence of seizures. Patients who develop priapism; peripheral vasculopathy including Raynaud's phenomenon. Closely monitor growth suppression in ped patients; interrupt treatment if patients are not growing or gaining height or wt. Do not administer w/ pre-existing severe GI narrowing (pathologic or iatrogenic). Periodic hematologic monitoring is advised during prolonged therapy. Patients w/ history of abnormally increased IOP or open angle glaucoma. Regularly monitor for onset or exacerbation of motor & verbal tics, emergence or worsening of tics or Tourette's syndrome during treatment. Pregnancy & lactation. Elderly >65 yr. Not to be used in childn <6 yr.
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