Colomycin Drug Interactions

Tell the doctor if the patient is taking, has recently taken or might take any other medicines.
If the patient is taking any of the following medicines, he/she may or may not be able to take Colomycin. Sometimes the other medicines must be stopped (if only for a while) or the patient may need a lower dose of Colomycin or may need to be monitored while he/she is taking Colomycin. In some cases, the level of Colomycin in the blood may have to be measured from time to time to make sure that the patient is having the right dose.
Medicines like antibiotics called aminoglycosides (which include gentamicin, tobramycin, amikacin and netilmicin) and cephalosporins which can affect how the kidneys function. Taking such medicines at the same time as Colomycin can increase the risk of damage to the kidneys (see Side Effects).
Medicines like antibiotics called aminoglycosides (which include gentamicin, tobramycin, amikacin and netilmicin) which can affect the nervous system. Taking such medicines at the same time as Colomycin can increase the risk of side effects in the ears and other parts of the nervous system (see Side Effects).
Medicines called muscle relaxants, often used during general anaesthesia. Colomycin can increase the effects of these medicines. If the patient has a general anaesthetic, let the anaesthetist know that the patient is having Colomycin.
If the patient suffers from myasthenia gravis and is also taking other antibiotics called macrolides (such as azithromycin, clarithromycin or erythromycin) or antibiotics called fluoroquinolones (such as ofloxacin, norfloxacin and ciprofloxacin), taking Colomycin further increases the risk of muscle weakness and breathing difficulties.
Having Colomycin as an infusion at the same time as receiving Colomycin as an inhalation can increase the risk of side effects.