Cledomox Special Precautions

CLEDOMOX should be given with caution to patients with lymphatic leukaemia since they are especially susceptible to amoxicillin induced skin rashes.
After administration of CLEDOMOX, if any allergic reactions occur, treatment should be discontinued and the appropriate therapy instituted.
Pseudomembranous colitis has been reported with nearly all antibacterial agents, including CLEDOMOX, and has ranged in severity from mild to life-threatening. Mild cases of Pseudomembranous colitis usually respond to drug discontinuation alone. In moderate to severe cases, consideration should be given to management with fluids and electrolytes, protein supplementation, and treatment with an antibacterial drug clinically effective against C. difficile colitis.
Change in liver function tests have been observed in some patients receiving CLEDOMOX. CLEDOMOX is contraindicated in patients with a previous history of cholestatic jaundice or hepatic dysfunction associated with CLEDOMOX. The onset of signs and symptoms of hepatic dysfunction may occur during or several weeks after treatment has been discontinued. The hepatic dysfunction which may be severe, is usually reversible.
Use in Pregnancy & Lactation: See USE IN PREGNANCY & LACTATION section for further information.