Sign Out
Incompatibility statement: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.
Additives may be incompatible with parenteral nutrition containing Cernevit.
If co-administration of drugs that are incompatible at the Y-site is necessary, administer via separate IV lines.
Vitamin A and thiamine in Cernevit may react with bisulfites in parenteral nutrition solutions (e.g., as a result of admixtures) leading to degradation of vitamin A and thiamine.
An increase in pH of a solution may increase the degradation of some vitamins. This should be considered when adding alkaline solutions to the admixture containing Cernevit.
Folic acid stability can be impaired with increased calcium concentrations in an admixture.
Instructions for Use/Handling: Aseptic conditions must be followed during reconstitution and when used as part of an admixture in parenteral nutrition.
Using a syringe, inject 5 ml of water for injections, or 5% glucose solution or 0.9% sodium chloride solution into the vial.
The obtained solution is yellow-orange in colour.
Mix gently to dissolve the lyophilized powder.
Before transfer from the vial, Cernevit must be completely dissolved.
Do not use unless the reconstituted solution is clear, the original seal is intact and the container is undamaged.
After addition of Cernevit to a parenteral nutrition solution, check for any abnormal colour change and/or the appearance of precipitates, insoluble complexes, or crystals.
Mix the final solution thoroughly when Cernevit is used as an admixture in parenteral nutrition.
Single use only. Any unused portion of reconstituted Cernevit should be discarded and should not be stored for subsequent admixing.
Use of a final filter is recommended during administration of all parenteral nutrition solutions.
