Sign Out
Hypersensitivity to the active substance or to any of the excipients listed in Description.
Known hypersensitivity to sulphonamides.
Active peptic ulceration or gastrointestinal bleeding.
Have experienced asthma, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria or other allergic type reactions after taking acetylsalicylic acid or other NSAIDs including COX-2 inhibitors.
In pregnancy and in women of childbearing potential unless using an effective method of contraception.
Breast-feeding.
Severe hepatic dysfunction.
Patients with estimated creatinine clearance < 30ml/min.
Inflammatory bowel disease.
Congestive heart failure NYHA II-IV.
Established ischemic heart disease, peripheral arterial disease and/or cerebrovascular disease.
In patient with severe heart failure.
For the treatment of peri-operative pain in the setting of coronary artery bypass graft surgery.
