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In therapeutic doses, no evidence of clinically significant interactions with other commonly used drugs has so far been observed. However, as with other NSAIDs, caution should be exercised in patients receiving oral anticoagulants, heparin via parenteral route and ticlopidine, thiazide diuretics, moclobemide, lithium, sulphonamide hypoglycemiant, methotrexate, pentoxifylline, zidovudine and baclofen.
Take into account interactions with antihypertensives (beta-blockers, conversion enzyme inhibitors, and diuretics), digoxin, and thrombolytics.
