Symptomatic relief of acute mucosal infections of the mouth & pharynx, & sore throat due to common cold & flu. Oral hygiene prior to, during & after dental & oral surgery.
Special caution when regularly applying to broken skin in patients w/ pre-existing renal insufficiency. Patients w/ goitre, thyroid nodules, or other non-acute thyroid diseases are at risk of developing hyperthyroidism; do not use for extended period (eg, not longer than 14 days) in this patient population unless strictly indicated. Monitor thyroid function. Do not use prior to or after radioiodine scintigraphy or radioiodine treatment of thyroid carcinoma. Do not heat prior to application. Avoid use during pregnancy & lactation unless potential benefit to mother justifies potential risk to foetus/neonate, or if safer alternative is unavailable.
PVP-iodine complex will react w/ protein & other unsaturated organic compd, leading to impairment of its effectiveness. Concomitant use w/ wound-treatment prep containing enzymatic components leads to weakened effect of both substances. Potential interaction w/ products containing Hg, silver, hydrogen peroxide, & taurolidine. Simultaneous use w/ Hg products may lead to formation of mucosa-damaging substance. May interfere w/ thyroid function tests or radioiodine therapy. Several tests for detecting occult blood in faeces or blood in urine may be affected (ie, false +ve results) due to the oxidative effect of povidone-iodine. Transient dark discolourations at application site when povidone-iodine is used before or after application of octenidine.
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