Discontinue use if irritation, sensitivity or other reaction develop and institute appropriate treatment. Corticosteroid applied to the skin can be absorbed in sufficient amount to produce systemic effects such as hypothalamic-pituitary-adrenal axis suppression, manifestation of Cushing's syndrome, hyperglycaemia and glucosuria. Thus suitable precautions should be taken during prolonged treatment, when treating extensive body surface areas, when using the occlusive technique and when treating children (because of larger skin surface area to bodyweight ratio). Safety of use of topical corticosteroids during pregnancy and lactation has not been established. Prolong use of a preparation containing an antibiotic may result in overgrowth of non susceptible organisms including fungi. If this occurs, discontinue use and institute appropriate therapy. Not suitable for ophthalmic use.
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