Avaxim 80/Avaxim 160

Avaxim 80/Avaxim 160

hepatitis a vaccine

Manufacturer:

Sanofi

Distributor:

Zuellig
/
Four Star
Concise Prescribing Info
Contents
Hepatitis A (GBM strain) vaccine (inactivated, adsorbed)
Indications/Uses
Avaxim 80 Prevention of infection caused by HAV in childn 12 mth to 15 yr of age. Avaxim 160 Prevention of infection caused by HAV in adults & adolescents ≥16 yr.
Dosage/Direction for Use
IM Avaxim 80 0.5 mL primary vaccination dose, followed by 0.5 mL booster dose 6 mth to 10 yr after 1st dose. Can be used as booster in subjects who have received 1st vaccination w/ another inactivated hepatitis A vaccine. Avaxim 160 0.5 mL primary dose, followed by booster dose 6-12 mth after 1st dose, & can be administered up to 36 mth after 1st dose. Can also be administered as booster dose of hepatitis A vaccine after receiving combined typhoid fever & hepatitis A vaccine 6-36 mth earlier.
Contraindications
Hypersensitivity to any component of the vaccine, or to neomycin, or following previous Avaxim inj. Postpone vaccination in case of febrile illness.
Special Precautions
Do not inj intravascularly, intradermally, & into the buttocks. Caution in patients on immunosuppressants (eg, corticosteroids, cytotoxic drugs, RT) or in a state of immune deficiency (eg, HIV infection); patients w/ liver disease; patients w/ haemophilia or those easily subjected to bruises or bleeding. Will not protect against hepatitis B, C or E viruses. May not work properly in patients w/ HAV infection at the time of vaccination. Contains phenylalanine, which may be harmful for patients w/ phenylketonuria. Do not use during pregnancy except in case of major contamination risk.
Adverse Reactions
Avaxim 80 Inj site pain; abnormal crying. Reduced appetite; irritability, insomnia; headache; stomach aches, diarrhoea, nausea, vomiting; muscle & joint pain; local inj site reactions eg, redness, swelling/induration, bruising; malaise, fever, fatigue/drowsiness. Avaxim 160 Mild inj site pain; fatigue. Headache; nausea, vomiting; loss of appetite; diarrhoea, abdominal pain; muscle & joint pain; mild fever.
Drug Interactions
Immunological response may be diminished in case of immunosuppressive treatment. Do not mix w/ other vaccines in the same syringe.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07BC02 - hepatitis A, inactivated, whole virus ; Belongs to the class of hepatitis viral vaccines.
Avaxim 80: P1S1S3, Avaxim 160: P1S1S3, A
Presentation/Packing
Form
Avaxim 160 susp for inj 160 u
Packing/Price
(pre-filled syringe) 0.5 mL x 1's
Form
Avaxim 80 susp for inj 80 u
Packing/Price
(pre-filled syringe) 0.5 mL x 1's
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