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Salbutamol and non-selective β-blocking drugs such as propranolol, should not usually be prescribed together.
Monoamine oxidase inhibitors, tricyclic antidepressants and digoxin increase the risk of cardiovascular effects.
Patients should be instructed to discontinue salbutamol for at least 6 hours before an intended anaesthesia with halogenic anaesthetics, wherever possible.
Hypokalaemia occurring with β2-agonist therapy may be exacerbated by treatment with xanthines, steroids, diuretics and long-term laxatives.
Because Asthalin Inhaler contains ethanol there is a theoretical potential for interaction in patients taking disulfiram or metronidazole. The amount of ethanol is small but it may be enough to precipitate a reaction in some sensitive patients.
